Transverse Myelitis

Disease/ Disorder Definition Transverse Myelitis (TM) is an inflammatory disorder of the spinal cord that may be idiopathic or related to other diseases.1,2 It is characterized by acute or subacute dysfunction of the spinal cord affecting the motor, sensory, and autonomic

Syringomyelia

Disease/ Disorder Definition Syringomyelia is an abnormal cystic collection of fluid, or syrinx that forms within the parenchyma of the spinal cord. Etiology There are two major types of syringomyelia: congenital or acquired1. Most cases of congenital syringomyelia are associated

Seizures and Epilepsy

[…] coping with seizure/epilepsy diagnosis. Professional Issues States differ in their requirements for reporting seizure/epilepsy diagnoses to the Office of Driver Services. Physicians should be knowledgeable of their local state law and regulations regarding drivers with an active history of epilepsy.14 […]

Agitation/Aggression/Apathy After Brain Injury and Other CNS Disorders

[…] variety of settings, including inpatient rehabilitation units, outpatient therapies, structured day programs, residential treatment, inpatient psychiatric treatment, and in-home cognitive services.28 Cognitive rehabilitation can be a particularly important part of functional recovery when agitation, aggression, or apathy occur. An international […]

Seronegative Spondyloarthropathy

[…] 10.3748/wjg.v25.i18.2162. PMID: 31143068; PMCID: PMC6526158. Denis Wakefield, John H. Chang, Shahriar Amjadi, Zoe Maconochie, Ahmed Abu el-Asrar & Peter McCluskey (2011) What Is New HLA-B27 Acute Anterior Uveitis?, Ocular Immunology and Inflammation, 19:2, 139-144, DOI: 10.3109/09273948.2010.542269 Ruiz DG, Azevedo MN, Lupi O. HLA-B27 frequency in a […]

Tendinopathy

Disease/ Disorder Definition Persistent tendon pain and loss of function related to mechanical loading1. May be acute but is typically a chronic overuse and degenerative condition, exacerbated by mechanical loading. Encompasses tendinitis, tendinosis, paratenonitis, and tendon ruptures2. Tendinitis typically refers

Sports Medicine Disorders of the Hip: Posterolateral

[…] 2010;468(7):1838-1844. doi:10.1007/s11999-009-1174-2 Blank E, Owens BD, Burks R BP. Incidence of greater trochanteric pain syndrome in active duty US military servicemembers. Orthopedics. 2012;35(7):e1022-e1027. Speers CJ, Bhogal GS. Greater trochanteric pain syndrome: a review of diagnosis and management in general practice. […]

Medial and Lateral Collateral Ligament Injuries

Disease/Disorder Definition The medial collateral ligament (MCL) and lateral collateral ligament (LCL) serve as stabilizers of the knee, providing both mediolateral stability as well as some degree of rotational stability. Injury to a ligament occurs when external forces applied to

Knee Osteoarthritis

[…] low lymphocytes and monocyte-macrophages), myeloid progressive (high NK and monocyte-macrophage lineage cells, low T-lymphocytes), and the aggressive phenotype (high cell lines throughout). Additional research is needed to understand the clinical significance of these phenotypes with regards to targeted therapeutic treatments.19 […]

Gout and Pseudogout

Disease Gout is a disease of purine metabolism characterized by acute, subacute, and chronic arthritis, due to deposits of needle shaped monosodium urate (MSU) crystals in joints, tendons, and subcutaneous tissues. Deposition of crystals leads to an acute inflammatory response